Antinuous

Medicine and clinical research

Test hundreds of trial designs before enrollment.

Antinuous simulates many trial designs and power scenarios at once and screens literature for systematic reviews with a log of each decision. Each number links to its study or the code that produced it.

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Use cases

Run a systematic review with an audit trail

Screening thousands of abstracts and extracting data from each study takes a team many months.

You ask

Find randomized trials of SGLT2 inhibitors in heart failure with preserved ejection fraction, extract hospitalization outcomes, and pool them in a meta-analysis.

What it does

  1. Searches PubMed and Europe PMC with a logged search strategy and flags retracted papers.
  2. Screens each abstract against your inclusion rules and records the reason for every exclusion.
  3. Reads included papers in full and extracts outcomes into a sheet, with each cell checked against its source.
  4. Runs the meta-analysis in the code workspace and writes it up in a literature review notebook.

You get

A notebook with a screening log, an extraction sheet and pooled results.

Records foundThousands
Abstracts screened inHundreds
Full texts readDozens
Studies includedA few

Each screening stage is logged with a reason.

Who it's for

Clinical researchersRun systematic reviews with a full screening log.
BiostatisticiansSimulate trial designs and power in a reproducible notebook.
Drug safety scientistsSee new safety reports and papers flagged as they appear.
Medical affairs teamsCompare a draft protocol with similar past trials.

Works with

PubMed
ClinicalTrials.gov
ChEMBL
PubChem
Slack
Google Slides

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Try Antinuous on your own research.
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